(released on September 2) is the twisted new sci-fi-horror flick that the actress both produced and stars in, alongside best friend Chloë Sevigny
. (Director Danny Perez, a longtime friend of both women, wrote the parts specifically for them.) Lyonne plays Lou,
a Midwestern junkie who could not give fewer fucks; Sevigny plays her BFF. Lou wakes up after a black-out night of hard-partying to figure out she's pregnant with, well, something. And at first, she's comically complacent about the fact that there’s a definitely-not-human thing growing inside her. “She’s just like, ‘Aw shit. Now I gotta fucking deal with this? Like, I just wanted to sit here and take bong hits,'” laughs Lyonne.
“Next thing you know, I’m caught up in this fucking interplanetary mission, and the thing is stuck in my body.”